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5 OMIM references -
4 associated genes
1 sign/symptom
PROTEIN INTERACTIONS: 1
2 associated genes
No signs/symptoms info
Familial progressive cardiac conduction defect
Complete atrioventricular canal - left heart obstruction

NKX2-5 CRELD1
SCN1B GATA4
SCN5A
TRPM4


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
NKX2-5
(0.96)
GATA4



Citations in the biomedical literature:


Familial progressive cardiac conduction defect
NKX2-5 SCN1B SCN5A TRPM4
Complete atrioventricular canal - left heart obstruction
CRELD1 GATA4



Familial progressive cardiac conduction defect
Complete atrioventricular canal - left heart obstruction

Synonym(s):
- Familial Lenègre disease
- Familial Lev disease
- Familial Lev-Lenègre disease
- Familial PCCD
- Familial progressive heart block
- Hereditary bundle branch defect

Synonym(s):
- CAVC - left heart obstruction
- CAVC type A
- Complete atrioventricular canal type A

Classification (Orphanet):
- Rare cardiac disease
- Rare genetic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare surgical cardiac disease

Classification (ICD10):
- Diseases of the circulatory system -
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: adulthood
Average age of death: elderly
Type of inheritance: autosomal dominant
Epidemiological data:
(no data available)

External references:
5 OMIM references -
No MeSH references
External references:
No OMIM references
No MeSH references

Familial progressive cardiac conduction defect

Frequent
- Cardiac rhythm disorder / arrhythmia



Complete atrioventricular canal - left heart obstruction

(no data available)